Thank you for the update Jeff. We think of you often and you are in our prayers. Yes the good news is the treatment options keep improving. My niece who was given 3 months to live 3 years ago is now in remission and living her best life. She was on the immuno therapy for about one year and yes severe side effects but Heather would say the side effects are nothing compared to her being here with her family. We will pray the next treatment with the Tamoxifen are effective. My mother-in law- Norma Corbett is currently on this drug for her cancer and She is certainly not experiencing side effects. God Bless your family. Love, Dorothy and Bob