Annabelle's diagnosis of a pilocytic astrocytoma was confirmed, and, more specifically, the tumor was found to have a genetic alteration called KIAA1549:BRAF fusion.
The plan moving forward is to treat with an oral MEK inhibitor called Trametinib. She will swallow capsules once per day. We will start with one, and depending on how she tolerates it, we will step up to three. The biggest concern about side effects right now is an acne-like rash. There are also eye health concerns and heart concerns. Her heart and eyes will be monitored while she is on Trametinib. She will have an echo-cardiogram coming up soon to set a baseline. She had an ophthalmologist exam after we got back from Memphis, so we should be able to use those records for the baseline on her eyes. If she has negative changes with her heart or eyes, we will stop the medication and the changes are expected to resolve.
Overall, I am relieved with the pathology results and having a plan in place. Thank you all so very much for your continued love and prayers!