Mine began 20 years ago. Small tan brown spots started to appear on my skin and I was sent for a biopsy where is was diagnosed with urticaria pigmentosa. At the time I only had a handful on my one leg and was told it was harmless, no treatment required and to go away and forget about it. Over the past few years these spot have multiplied and spread. I frequently felt nauseous and then other unexplained things started to happen.