Feb 27, 2019 Latest post:
Jun 20, 2020
I was diagnosed with intrahepatic cholangiocarcinoma, also known as bile duct cancer, in January 2019. The historical survival 5 years after diagnosis has been 1 in 10, a rather dismal prognosis. Thankfully, I have benefited from excellent care including partial hepatectomy (75% of liver was removed), radiation for bone metastasis and two different chemotherapies for liver metastases. In November of 2019, I was enrolled in a clinical trial of a new targeted therapy against FGFR2, the driver mutation identified by genomic analysis. After more than160 days on the oral FGFR inhibitor TAS-120 my liver mets are small and stable in size and I feel well. Given this level of response, the expectation is I may remain on this therapy without progression for months, even years. Cautiously optimistic, it's time to return to living my life: covid-19 shelter in place. I'll take it.