Dale Statz

First post: Mar 8, 2022 Latest post: Jul 16, 2022
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Following my annual routine physical in early September 2021, and after a series of follow up tests and bone marrow biopsy, I was diagnosed with Myelofibrosis (MF); a rare bone marrow disease (considered to be a chronic leukemia), which is a progressive disease; I am in a high risk stage. One in 100,000 of the population are diagnosed with MF; the cause is unknown. 
My MF has a JAK2 gene mutation; my dx is typically referred to as that - JAK2 disease; which creates scar tissue in the bone marrow. The JAK2 protein is important for controlling the production of blood cells from stem cells. These stem cells are located within the bone marrow and have the potential to develop into red blood cells, white blood cells and platelets. My initial treatment will be taking the drug Jakafi; which is a JAK2 Inhibitor; targeted treatment that works to keep the production of blood cells under control. I started taking this Rx the end of October; and have experienced no side effects to date. Jakafi is not a cure for JAK2; over time JAK2 leads to progressive bone marrow failure. There will come a time my only option for a possible cure will be a allogenic stem cell transplant. 

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