My Story

Chris Sanderson, age 38, was diagnosed with a grade IV glioma, malignant brain tumor, Glioblastoma Multiforme in December 2008. He has a wife, Brogann, and two little girls, Stevie (6) and Clementine (4). He coaches professional lacrosse and runs his own lacrosse business.


Please use this site to channel positive energy and words of encouragement to Chris and his family.

10/15/08 grand mal seizure, MRI – benign tumor left frontal/temporal lobe grade 1

12/9/08 MRI – significant growth concerning for GBM

12/22/08 Craniotomy with gross total resection at Duke University Medical Center by Dr. Allan Friedman, pathology GBM

1/12/09 – 2/23/09 6 weeks radiation therapy w/ Dr. Lustig at UPENN with concurrent low dose Temodar and Avastin every 2 weeks

3/17/09 Started on patient specific regimen including EGFRvIII peptide vaccine, Temodar 200mg/m@ daily for 5days/mo, Bevacizumab 10 mg/kg every 2 weeks.  Care managed for 2 years by Dr. David Reardon (Duke, later Dana Farber) and Dr. Peter Phillips (CHOP/UPenn).

3/14/11 s/p 24 cycles of Temodar 200 mg/m2 for 5 days/mo and s/p 27 doses of Avastin every 2 weeks.  MRI showed enhancement, PET showed increased metabolic activity.  Biopsy to confirm recurrence scheduled with Dr. Friedman at Duke.

3/17/11 biopsy of left temporal area by Dr. Friedman at Duke.  Pathology c/w recurrent GBM, MGMT promoter methylated, IDH 1 negative

3/25/11 Gross total resection by Dr. John Yu at Cedars-Sinai Medical Center.  Dendritic Cell Vaccine with Imiquimod started.

4/13/11-4/15/11 Radiosurgical boost by Dr. Lustig and UPenn while awaiting vaccine trial

5/13, 5/27, 610/11 Dendritic Cell Vaccine with Imiquimod trial at Cedar-Sinai Medical Center.  Discontinued trial and resumed Avastin.

7/28/11 Resumed systemic therapy with Avastin with Dr. Reardon at Dana Farber Cancer Institute.  Daily Etoposide and daily Verinostat both attempted but poorly tolerated and discontinued.

11/15/11 MRI showed new enhancement.

12/20/11 Underwent biopsy with injection of Tocagen and started Flucytosine regimen as part of Tocagen trial with Dr. Vogelbaum.  2 doses of Flycytosine until 2/22/12

3/15/12 MRI showed tumor progression.  Tocagen trial discontinued.

3/22/12 Craniotomy, partial resection (approx. 60%) debulking by Dr. Don O’Rourke at Hospital of the University of Pennsylvania.

4/12/12 Intraarterial Erbitux/Cetuximab infusion trial by Dr. John Boockvar at Weill Cornell Medical Center

4/26/12 Novocure Device, JFK Hospital in Edison NJ, Dr. Landolfi

5/15/12 Antisense trial, Dr. David Andrews, Thomas Jefferson University Hospital, Philadelphia, PA


Brogann Sanderson posted a new journal entry, "Help for the Family -From Mark".

Hi Everyone, its Brogann’s brother Mark.  As many of you know, a large portion of Chris and Brogann's family will be traveling long distances to support and say goodbye ... Read more

Brogann Sanderson posted a new journal entry, "TIME TO SAY GOODBYE".

Chris is not doing well.  I brought him down to Jefferson on Tuesday after a sleepless night of trying to manage his headache pain unsuccessfully.  It was a very ... Read more

Brogann Sanderson posted a new journal entry, "UP AND DOWN AND ALL AROUND".

It has been a very emotional few days since Chris arrived home from the hospital.  Truthfully, I cannot make sense of everything that is going on, so I am just going to ... Read more

Brogann Sanderson posted a new journal entry, "AND WE'RE BACK...".

... AT THE HOSPITAL! Yesterday morning Chris complained of severe nausea, drastic and sudden vision impairment, overall weakness, and some minor disorientation.  Just ... Read more

Brogann Sanderson posted a new journal entry, "HOME, BUT NOT WITHOUT DRAMA".

Chris has been home for about 24 hours.  He was discharged on an antibiotic called Keflex which he has now been taking for about 48 hours.  While we are happy to have ... Read more

Brogann Sanderson posted a new journal entry, "ROLLERCOATER INDEED".

So, Chris is back in the hospital, this time with a bizarre combination of symptoms pointing to two different unrelated infections -- 1) an internal infection between the ... Read more

Brogann Sanderson posted a new journal entry, "Jefferson Trial MRI #1".

I have so much ground to cover in this update.  Where do I even begin?  I guess I will start with today and work backwards.   Today marks 14 days from Chris's initial ... Read more

Brogann Sanderson posted a new journal entry, "COMING HOME".

Chris is doing well and everything continues to run smoothly here at Jefferson.  The two abdominal surgeries went seamlessly and Chris is feeling pretty good.  He got ... Read more

Brogann Sanderson posted a new journal entry, "DOING WELL".

Last night was better than I expected.  We had a rough stretch in the earlier part of the evening -- there were a few hours during which Chris was extremely agitated and ... Read more

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