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Emma’s Story

Emma was diagnosed with metastatic Osteosarcoma~ July 8, 2009...

In April 2009, Emma complained of pain in his left leg above the knee.  She had been skiing and cycling alot, so we thought this was an orthopedic issue.  We took Emma to the orthopedic surgeon for x-rays & nothing was found.   4 wks. of physical therapy, ice, and ibuprofin were prescribed, then an MRI if pain hadn't dissipated.  Pain decreased, so we thought p.t. was helping; in fact, a tumor had broken out of the bone, which can relieve pain.  3 wks. after seeing the orthopedist, at a routine visit to the pediatrician, Emma was advised to get the MRI.  On July 6th, the scan revealed a mass in her left distal femur;  within 2 hours she was admitted to CHLA.  At the age of 13, on July 8, 2009, Emma was diagnosed with metastatic osteosarcoma (bone cancer).  A single, marble-sized tumor was also found and removed by thoracoscopy from his left lung.  Emma completed 6 MAP treatments, then had surgery to remove the tumor on her leg on October 2, 2009.  The femur was replaced with a Compress prosthesis and artificial knee.  Pathology was 75% necrosis; clear margins.  18 total chemo treatments were completed Feb. 28, 2010, with no evidence of disease (NED).

June, 2010, 
Emma had a boating accident at camp.  July 5, 2010 he had a complete revision of the prosthesis (July 5, 2010). 

September 14, 2010 6 mo. scans revealed a tumor in upper left lung.  Sept. 20, 2010-  thoracotomy; total of 4 tumors found, 3 in the pleural cavity; clear margins.  Treatment consisted of 10 rounds chemo (Ifosfomide, Etoposide), the trial drug L-MTP-PE, and radiation to the lung.  Completed: May 15, 2011- Ifos/ Etop; June 24, 2011- radiation; & L-MTP-PE- June 28, 2011.

July 16, 2012- 15 mo. scans reveal 2 cm. tumor in lower right lung.  July 22, 2012- thorocotomy; 2 tumors found;  lobectomy of lower right lung; clear margins. Gemcitabine/Docetaxel completed January 2013.

February 2013 began Hu3F8/IL-2 trial at MSKCC in New York.

We can't begin to express our gratitude for all the messages of support we've received!

Debbie, Roy, 
Emma, and Bo Knickman


Latest Journal Update

Clear Scans

Scans clear today. Another month of chemo down. Many more to still to come. ANC is still down so chemo will be backed up one week. Making the 6 month mark since the last recurrence is a very positive sign. The normal progression is quicker and quicker recurrences. There was 4 months between the last two, but now Emma is at 6 months. Emma is tired and the side effects seem to last longer each treatment, but Emma willing to endure.

Thanks for the continued support.

43 people hearted this



Sharon Berry
By Sharon Berry
I think of Emma so often. I would really like an update. Anyway uou are all still in my prayers.
Polly Derr
By Polly Derr
You are in my prayers as always!
wendy marcuson
By Wendy
Emma is still fighting and has not had a recurrence ! I couldn't wait any longer and checked FB :)
Linda Zerangue
We have not heard any news of Emma for so long and fear that the treatments did not work for her. If that is so we will continue to pray for her family in their grief. Linda and Don Zerangue
1 person hearted this
Denise Kaufman-McDaniel
By Denise Kaufman-McDaniel
Still thinking of you and adding my thoughts & prayers for comfort, healing and peace along with those of so many others. The battle, the can be so wearing. Please know that you have the love and support from so many as you chose how to face each day of your life. A hug to you - through the miles - from the mother of another brave, kind, wonderful osteo warrior.
Susi Wissink
By Susi Wissink
I just wanted you to know that people are still following you and care about how you are doing. Hang in there, Emma.
Linda Zerangue
We are thinking of you and praying for continued courage and a cure for Emma. The Zerangues
Susi Wissink
By Susi Wissink
Clear scans are such great news. Sometimes all you can do to get through the day is endure. That in itself is success.
judy mescon
YAY!!!!!!!!! So happy for good scan news. Hang in there Emma, (and Roy and Deb and Bo too)'ve been through waaaay too much, but hopefully this chemo will keep you LONG NED! or better yet, forever NED!
mom to Jenna
Candida Stoutenborough
By Candida Stoutenborough
It is always so good to hear those words..."clear scans." We continue to keep you all in our prayers...and especially you, Emma, for all the pain and suffering you have to constantly go through. One day at a will get there!

Love, Candy