Alexa was our 4-year-old little girl who was diagnosed with neuroblastoma stage IV on December 12, 2005. Alexa received protocol treatment at the Children's Medical Center of Dallas until May of 2006 when it was determined that her cancer was not responding. In July we took her to CHOP in Philadelphia to take part in a clinical study involving MIBG therapy and a bone marrow transplant to try to save her life. Sadly it did not work and the cancer had spread. She was not expected to live past Christmas. In January, we discovered she had a delayed reaction to the treatment, so we tried a Phase II clinical trial involving humanized anti-body therapy. Alexa had a major allergic reaction to the medicine, so we were unable to continue the treatment. We took her back to CHOP for another MIBG therapy and then spent 10 months on a phase II clinical trial oral chemo called ABT-751. In May 2008 she started having fevers and on June 25, 2008 she passed away in our arms in the ICU at Children's in Dallas from an unidentified infection in her lungs. We found out later it had also spread to her liver and her kidneys had lost so much oxygen they were almost in failure as well. There was nothing we could have done. I guess it was her time to go, but I would give anything to have her back.